Agbas, Abdulbaki

Abdulbaki Agbas

PhD, MSc
Professor of Biosciences


  • Ph.D. in 1988, University of Szeged/ Szeged-HUNGARY, 1988
  • M.Sc. in Biochemistry, Ataturk University/Erzurum-TURKEY, 1985
  • B.S. in Chemistry, Ataturk Univeristy/ Erzurum-TURKEY, 1980

Teaching Interests/Courses

  • Citric Acid Cycle
  • Mitochondrial Bioenergetics
  • Oxidative Phosphorylation
  • Regulation of Oxidative Phosphorylation
  • Protein Folding-I,II,III

Research Interests

  • Exosomal TDP-43 and its derivatives in neurodegenerative diseases. A blood based biomarker development
  • Effect of oxaloacetate in lifespan of ALS-model mouse
  • Development of Biomarkers for Alzheimer's Disease and Amyotrophic Lateral Sclerosis
  • Mitochondrial Bioenergetics in Neurodegeneration
  • Zinc Homeostatis in Motorneurons
  • Molecular Biology of Aging and Neurodegeneration


    The goal of this proposal is to test if a canine degenerative myelopathy (DM) can be utilized as a disease model to develop a viable blood-based biomarker for human amyotrophic lateral sclerosis (ALS). Canine DM is a progressive, adult-onset, multi-s, 04/2020 - Present
  • Baseline platelet mitochondrial respiration rate in diabetic patients with neuropathy
    The overarching idea in this proposal is that reduced mitochondrial function can be assessed by whole platelet respiration which will provide monitoring tool for the prognosis of DPN as well as implementing the therapeutical interventions, 11/2017 - 06/2019
  • Platelet TDP-43 protein: A proxy for proteinopathy in Alzheimer's disease
    Developing a peripheral biomarker/surogate marker that can be used for early detection of Alzheimer's disease before the clinical manifestations are revealed, 08/2013 - 08/2014


  • Cellular Bioenergetics Master Class
    Joined the bioenergetics hands on classes to master my understanding about the mitochondria biochemistry, 04/2018
  • Molecular Biology of Aging course
    A three-week lecture and laboratory course featuring the newest and most exciting ideas in aging research, with emphasis on molecular approaches. A distinguished faculty interacted with students via lecture, discussion and hands-on experiments, 07/2001
  • International Training Course Fellowship in Modern Biology
    Trained in modern biological topics, 09/1988

Professional Affiliations

  • Member, 01/2012 - Present, American Association for the Advancement of Science


  • Member, 01/2012 - Present, The American Society for Cell Biology


  • Member, 01/2012 - 12/2012, Society for Neuroscience


Physician Specialties

  • Mitochondria Physiology
  • Neurobiology (Motor Neurons and Astrocytes)
  • Protein Biochemistry

Community Service

  • Science Mentor, 11/1/2013 - Present, Science Pioneer, Inc.
    I met several high school students and discussed their science projects.


Outside Interests

  • Archery
  • Playing Reed Flute (Nay)
  • Reading (Historical and philosophical books)